Particle Technology
Magnetic Particles
· Sera-Mag® Magnetic Particles
Nonmagnetic Particles
· Power-Bind™ Streptavidin
Microparticles (SA-MP)
Polystyrene Particles
· OptiBind® Polystyrene
Microparticles (PS)
· OptiLink® Carboxylate-Modified
Polystyrene (CM)
Dyed Particles
· Color-Rich™
Dyed Polystyrene
· Fluoro-Max™ Fluorescent
Carboxylate-Modified


Patened Solid Phase Reversible Isolation (SPRI®) with Sera-Mag® Magnetic Particles

Sample prep – the first step

  
· Agencourt
· SPRI Data Sheet (PDF)
· Microparticle Application
  and Usage Chart
· Material Safety Data Sheets
· Product Technical Notes
· Application Notes / Protocols
· Product Manuals
Sera-Mag® Magnetic Particles
Applications


  • Molecular Biology
    - DNA probes
    - Isolate PCR product
    - Sample prep
  • Immunoassay
    - Chemiluminescent
    - Radio-labeled
    - Capture
  • Cell Isolation
    - CD4/CD8
    - Etc.
Sera-Mag® Magnetic Carboxyl
Patented SPRI Process 5,898,071
  • Solid Phase Reversible Isolation
  • Non-specific isolation
    of polynucleotides
  • Isolation based on size
  • Isolation applications for
    - DNA
    - RNA
    - PNA


Sera-Mag™ Magnetic Carboxyl
Patented SPRI Process 5,898,071		 Magnetic-Based Isolation Systems
SPRI Applications
  • dsDNA from plasmids
  • dsDNA from cosmids
  • ssDNA from clones
  • DNA isolation from gels
  • Advantages over silica
    - Better performance
    - Better yield
    - Cleaner preparations
    - Lower non-specific binding

  • Whitehead (Broad) Institute
  • Joint Genome Institute
  • Curagen
  • Lawrence Livermore
  • Los Alamos
  • Bristol-Meyers Squibb

  • Washington University
  • Agencourt Bioscience
  • Packard
  • University of Utah
  • Aventis
  • NIH Sequencing Center


SPRI Methods Technology
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